CLEMSON, S.C. -- James Conners smile said it all -- Pittsburgh was happy to once again shuffle up the national championship picture.Hey, sorry to do that. But we wanted this one bad, said Conner, who had two touchdowns and ran for 132 yards in the Panthers 43-42 stunner over No. 3 Clemson on Saturday.Conners 20-yard TD run with 5:17 left inched the Panthers into striking range and Chris Blewitt -- after a kiss on the cheek from coach Pat Narduzzi -- struck a perfect, 48-yard field goal with six seconds left for the winning points.Well remember this one forever, Conner said.So, too, will Clemson (9-1, 6-1 Atlantic Coast Conference) which saw its run at perfection halted after escaping so many other jams this season. A fourth-down stop a yard shy saved the Tigers 42-36 win over No. 5 Louisville on Oct. 1. North Carolina States missed field goal at the end of regulation boosted Clemson to a 24-17 overtime win.This time, it was the Panthers (6-4, 3-3) who made the critical plays.When Clemson was driving for a touchdown already up 42-34, linebacker Saleem Brightwell picked off quarterback Deshaun Watson -- his third interception -- and returned it 70 yards to set up a 20-yard TD by Conner that drew Pitt within 42-40.When Clemson attempted to run out the clock, the Panthers defense (despite allowing 630 yards) stuffed Wayne Gallman a yard short on third and fourth downs to take over near midfield with 58 seconds left.We had a chance to put the game away and they stopped us, Clemson coach Dabo Swinney said. We had been making those kinds of plays this year.Nathan Peterman moved Pitt to the Clemson 30 and Blewitt steadily knocked through.It was Pitts highest-ranked win since defeating Backyard Brawl rival, No. 2 West Virginia, 13-9 in 2007 and spoiling the Mountaineers chances at playing for the national title.Our team had a lot of guts tonight, Narduzzi said.And a whole lot of playmakers to topple the defending ACC champs.Peterman had a career-best five TD passes and 308 yards. Conner rushed for 132 yards and a touchdown. He also caught one of Petermans scoring throws.Blewitt, who had a kick blocked at the end of the opening half, was steely eyed and ready. Narduzzi gave his senior a kiss on the cheek and sent him out for the winning kick.As soon as I saw the kick go up, I knew it was going in, Scott Orndoff said. It was jubilation.Clemson had its offense going. Watson threw for an ACC record 580 yards and three touchdowns. Gallman ran for three TDs and Mike Williams had 15 catches for 202 yards and a touchdown.In the end, it was Clemsons first loss to an unranked opponent in five seasons, a span of 46 games.Come Monday, well start over because its a long season, Watson said. Get ready for Wake Forest. Hopefully, we can clinch the ACC (Atlantic) and punch our ticket for the championship game next week.THE TAKEAWAYPittsburgh: The Panthers showed that Narduzzis program is taking hold. Peterman stayed calm in the face of Clemsons strong pass rush and Conner was able to avoid the Tigers middle duo of Carlos Watkins and Dexter Lawrence to keep Pitt moving.Clemson: Many non-Tiger fans will say this team had it coming after escaping with close wins at home against No. 5 Louisville (42-36 on Oct. 1) and North Carolina State (24-17 in overtime on Oct. 15) after the Wolfpack missed the potential game-winning kick to end regulation. Clemsons path is still clear -- win out and hope its one-loss season is better than most others.POLL IMPLICATIONSA rankings fall seemed likely for Clemson after the loss but that is likely to be mitigated by losses suffered by No. 2 Michigan and No. 4 Washington later in the day. After Wake Forest, the Tigers face revived rival South Carolina at Death Valley before potentially heading to Orlando, Florida, for the ACC championship game.RECORD DAYWatsons passing yards broke the 21-year-old mark of Wake Forests Rusty LaRue, who passed for 545 yards against North Carolina State on Nov. 18, 1995. Watson said the record doesnt console him after the loss. Id rather go 0-for-30 with no yards and get the W, he said.SAYING GOODBYEThis wasnt the farewell Clemsons offense wanted. Watson, Gallman, Williams and receiver Artavis Scott are all juniors who were honored with Clemsons seniors Saturday after Swinney said they would all be leaving the program for the NFL after this season. Watson acknowledged wild emotions. Still, Im going to keep a smile on my face, he said.UP NEXTPittsburgh closes the year with two games at home, starting with Duke next week.Clemson will try to earn the ACC Atlantic Division title with a win at Wake Forest next Saturday.---More AP college football: www.collegefootball.ap.orgFake NFL Jerseys Free Shipping . Speaking to the Chicago Tribune at baseballs Winter Meetings in Lake Buena Vista, Florida, Boras called the former home of the Expos a "tremendous environment" for baseball. Fake NFL Jerseys For Sale . The visitors took a deserved lead in the 16th minute with midfielder Yohan Cabaye curling the ball beyond Adrian from inside the penalty area. https://www.fakenfljerseys.com/ . The CFLs leading rusher kept adding to his gaudy numbers this season and scored the winning touchdown with just over two minutes to play. The New Westminster, B.C., native plowed three yards into the end zone for the last score of a heated, see-saw battle between the two teams with the best records in the CFL. Fake Nike NFL Jerseys .Y. -- Sabres forward Drew Stafford has witnessed plenty of turmoil during his eight seasons in Buffalo. Fake NFL Jerseys Cheap . Parker had 26 points and eight assists and San Antonio beat Toronto 112-99 Monday night. "We won that game because of Tony Parkers aggressiveness," Spurs coach Gregg Popovich said. "His juice; his aggression all night long.PHOENIX -- The Arizona Diamondbacks looked headed for a seventh straight loss and more disappointment at home. Then Welington Castillo brought smiles and relief.The catchers three-run homer in the eighth inning rallied Arizona to a 6-5 victory over the San Francisco Giants on Saturday night.Castillo ripped reliever Hunter Stricklands 2-1 pitch into the stands in left field with one out. The Giants led 5-3 going into the inning, but starter Jeff Samardzija and reliever Josh Osich each put runners on base.I just was waiting for something over the plate and close to me that I can put a good swing on it, Castillo said. It means a lot, especially here at home.Strickland (3-1) replaced Osich and gave up the games biggest hit.I tried to throw a two-seamer, left it over the plate and it didnt move. I would say he got the best of it, Strickland said. I was trying to throw it in. I was trying to get a ground ball.Jake Barrett (1-0) earned his first major league win in relief and Brad Ziegler got his 17th save of the season.Brandon Crawford and Mac Williamson hit back-to-back home runs to give the Giants a 5-1 lead in the fourth. Williamsons blast flew well over the 413-feet sign in left-center field and off the bottom left corner of the Chase Field video board.The Diamondbacks avoided their longest losing streak of the season.Its huge. It flips the whole thing around, manager Chip Hale said. We got the one pitch from Strickland and did some damage to it.Diamondbacks first baseman Paul Goldschmidt made a diving stop and putout to end the game with a runner on first for the Giants.That is one we let get away, Giants manager Bruce Bochy said.The Giants scored their first three runs in the second inning. Buster Posey walked, took third on a single and scored on a fielders choice when Diamondbacks shortstop Jean Segura threw wide to home plate for an error after fielding Williamsons grounder.Recent callup Ruben Tejadas first hit and RBI as a Giant came one out later, on a single to drive in Crawford. Then Samardzija grounded to Segura, who bobbled the ball and could only get one out to allow Williamson to score.Patrick Corbin doubled and scored in the fourth thanks to teammate Michael Bourns hustle. Bourn beat out what looked to be an inning-ending double-play grounder at first base, allowing Corbin to score from third.Castillo and Chris Herrmann doubled in runs in the fifth -- Herrmanns drive close to being a home run to right-center field -- to cut the Giants lead to two.Hale was ejected before the top of the seventh inning, arguing with home plate umpire Brian Knight soon after Herrmann was called out on strikes.ddddddddddddIt was Hales second ejection of the season.ITS A BOYDiamondbacks infielder Nick Ahmed is on paternity leave after the birth of his first child, a son. Ahmed left Fridays game before it ended to be with his wife Amanda, and could return to the team by Monday.The Diamondbacks made a roster move to replace Ahmed before Saturdays game, recalling reliever Enrique Burgos from Triple-A Reno.RETURN IMMINENTDiamondbacks outfielder Rickie Weeks Jr. is expected to return from bereavement leave on Sunday, at which time the team will make another roster move to add him, Hale said. Weeks has been away from the team since Thursday.TRAINERS ROOMGiants: OF Denard Span got another day off due to neck stiffness but could be back by Sunday. ... OF Hunter Pence (hamstring strain) took on-field batting practice Saturday. Hes been on the 15-day disabled list for a month. ... Starting pitcher Matt Cain was scheduled to throw 45 pitches in a minor-league game Saturday as he returns from a hamstring strain. ... INF Ramiro Pena (ankle) was available for pinch-hitting duty Saturday. ... 2B Joe Panik (concussion) is still resting and is eligible to return Tuesday.Diamondbacks: Hale said ace Zack Greinke felt better during Fridays game, and the team has yet to decide whether to place Greinke on the disabled list with a left oblique injury. Greinke was expected to undergo a scan Saturday to determine if he has a strain. Greinke could pitch as soon as next weekend if all is well and can still be named an NL All-Star, but may not pitch in San Diego. ... OF David Peralta and OF-IF Chris Owings, both on the 15-day disabled list, are moving closer to being able to play in games. They could be back in action after the All-Star break, Hale said. OF Socrates Brito (fractured toe) is also close to returning from the DL.UP NEXTGiants: Sundays scheduled starter is Albert Suarez (3-1, 3.83 earned run average), who is in the rotation in place of Cain. Hes done such a great job in whatever role weve put him in, Bochy said.Diamondbacks: Sunday starter Robbie Ray (4-7, 4.69 ERA) is 1-0 with a 1.64 ERA in two starts against the Giants in his career. He is averaging 10.42 strikeouts per nine innings pitched, which is in the top 10 in the NL. ' ' '